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Printable Version Methadose Tablets

Active Ingredients: Methadone
Other Names: Dolophine Tablets, Methadone Hydrochloride Tablets, Methadose Tablets
Rx Status: Available by prescription only
Generic Available: Yes
Product Images & Descriptions:

What is/are Methadose Tablets?
What should I tell my health care providers before I take this medicine?
How should I use this medicine?
What if I miss a dose?
What may interact with this medicine?
What side effects may I notice from this medicine?
What should I watch for while using this medicine?
Where should I keep this medicine?

What is/are Methadose Tablets? (Back to top)
METHADONE is a pain reliever. It is used to treat severe pain. The medicine is also used to prevent withdrawal symptoms in people addicted to other drugs. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.


What should I tell my health care providers before I take this medicine? (Back to top)
They need to know if you have any of these conditions:

  • brain tumor
  • drug abuse or addiction
  • head injury
  • heart disease
  • frequently drink alcohol-containing drinks
  • kidney disease or problems going to the bathroom
  • liver disease
  • lung disease, asthma, or breathing problems
  • mental problems
  • an unusual or allergic reaction to methadone, other opioid analgesics, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine? (Back to top)
Take this medicine by mouth with a drink of water. If the medicine upsets your stomach, take it with food or milk. Follow the directions on the prescription label. Do not take more medicine than you are told to take.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.


What if I miss a dose? (Back to top)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.


What may interact with this medicine? (Back to top)
Do not take this medicine with any of the following:

  • antibiotics like chloroquine, clarithromycin, erythromycin, grepafloxacin, pentamidine, sparfloxacin, troleandomycin
  • arsenic trioxide
  • cisapride
  • droperidol
  • halofantrine
  • haloperidol
  • medicines for irregular heart beat like amiodarone, bretylium, disopyramide, dofetilide, procainamide, quinidine, sotalol
  • pimozide
  • ranolazine
  • rasagiline
  • selegiline
  • sertindole
  • ziprasidone

This medicine may also interact with the following:
  • alcohol
  • alfuzosin
  • antibiotics like gatifloxacin, gemifloxacin, levofloxacin, mefloquine, moxifloxacin, ofloxacin, telithromycin
  • antihistamines for allergy, cough and cold
  • desipramine
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for irregular heart beat like flecainide, propafenone
  • medicines for nausea or vomiting like dolasetron, ondansetron, palonosetron
  • medicines for seizures like carbamazepine, phenobarbital, phenytoin
  • medicines for sleep
  • medicines for sleep during surgery
  • medicines to numb the skin
  • muscle relaxers
  • narcotic medicines for pain
  • octreotide
  • peginterferon Alfa-2b
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • rifampin, rifapentine
  • some medicines for cancer like dasatinib, lapatinib, sunitinib
  • some medicines for HIV like delavirdine, didanosine, efavirenz, nevirapine
  • St. John's wort
  • tacrolimus
  • tramadol
  • vardenafil
  • vorinostat

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.


What side effects may I notice from this medicine? (Back to top)
Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • chest pain
  • confusion
  • feeling faint or lightheaded, falls
  • unusually fast or slow heartbeat
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
  • nausea, vomiting
  • sweating

This list may not describe all possible side effects.


What should I watch for while using this medicine? (Back to top)
Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take this medicine for a long time.

Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

You may get drowsy or dizzy when you first start taking this medicine or change doses. Do not drive, use machinery, or do anything that may be dangerous until you know how the medicine affects you. Stand or sit up slowly.

This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.


Where should I keep this medicine? (Back to top)
Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and is against the law.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.


Last Updated:October 23, 2007

COPYRIGHT© Gold Standard, An Elsevier Company


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.

  Additional Information

  Check Drug Interactions with Methadose Tablets

  Test Yourself! If you currently take Methadose Tablets, do you know everything that you need to know?

  Make your own printable Medication / Emergency Contact Card



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